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Clinical Biochemistry

Clinical Biochemistry is the division of laboratory medicine that deals with the measurement of chemicals (both natural and unnatural) in blood, urine and other body fluids. These test results are useful for detecting health problems, determining prognosis and guiding the therapy of a patient.

Clinical Biochemists are PhD level scientists with specialized post-doctoral training in laboratory medicine. All hold certification from the Canadian Academy of Clinical Biochemistry or equivalent. Ongoing professional competence is ensured through participation in the Maintenance of Competence program offered by the Academy.Clinical Biochemists ensure that consistent high quality, accurate and precise biochemical test results are provided so that high quality care can be provided to the patient. Clinical Biochemists lead the development and implementation of laboratory quality management systems that encompass all aspects of the testing process: pre-analytical, analytical and post-analytical.

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  • Interpretation of patient laboratory tests for screening, diagnosis, management and monitoring of disease processes.
  • Development of interpretive guides for other professionals using the laboratory service, through the selection and validation of reference intervals, interpretive comments and critical values.
  • In consultation with clinical colleagues, development, implementation and monitoring of testing algorithms, appropriate testing turnaround times, practice guidelines and care pathways.

Biochemical tests are most often applied to samples of serum, plasma and urine where levels of specific chemicals are measured and the results compared with those representative of a healthy individual. An increase or decrease in any particular component(s) can help to identify a disease process.

In clinical biochemistry, working as a clinical scientist, you'll help to diagnose and manage disease through the analysis of blood, urine and other body fluids. You'll do this by producing and validating the results of chemical and biochemical analyses.

To work in clinical biochemistry, you'll need: an interest in science and technology, a good academic background and an ability to update and test your knowledge against experience. good communication skills and be able to liaise with the healthcare team and also to advise and reassure patients.